Mutation Information
Mutation Site
|
M204I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Combined Mutation
|
rt.M204I+rt.L180M+rt.A194T;rt.M204I+rt.S202C+rt.T184L+rt.L180M+rt.L80I+rt.A194T;rt.M204I+rt.S202G+rt.T184L+rt.L180M+rt.L80I+rt.A194T;rt.M204I+rt.A181T+rt.A194T;rt.M204I+rt.A181T+rt.L80V+rt.A194T;rt.M204I+rt.A181T+rt.L80I+rt.A194T;rt.M204I+rt.D134E+rt.H126Y+rt.S106C;rt.M204I+rt.L180M+rt.L80I+rt.D134E+rt.H126Y+rt.S106C;rt.M204I+rt.L180M+rt.L80I+rt.L269I+rt.D134E+rt.H126Y+rt.S106C;rt.L229M+rt.M204I+rt.L269I+rt.D134E+rt.H126Y+rt.S106C |
Relevant Drug
|
lamivudine (LAM);entecavir (ETV);adefovir dipivoxil (ADV);tenofovir (TFV);tenofovir alafenamide (TAF) |
Literature Information
PubMed PMID
|
32894807
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2021 |
Journal
|
Journal of viral hepatitis |
Title
|
Characterization of Hepatitis B virus polymerase mutations A194T and CYEI and tenofovir disoproxil fumarate or tenofovir alafenamide resistance. |
Author
|
Liu Y,Chang S,Martin R,Flaherty J,Mo H,Feierbach B |
Evidence
|
TABLE 3
|
|
|