|
Mutation Information
|
Mutation Site
|
L217R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Amino acid_Mutation
|
T880G |
|
Genotype/Subtype
|
E |
|
Relevant Drug
|
adefovir (ADV) |
|
Country
|
Argentina |
Literature Information
|
PubMed PMID
|
22967107
|
|
Disease
|
HBV infection
|
|
Published Year
|
2012 |
|
Journal
|
Journal of viral hepatitis |
|
Title
|
Specific primer sets used to amplify by PCR the hepatitis B virus overlapping S/Pol region select different viral variants. |
|
Author
|
Cuestas ML,Mathet VL,Oubiña JR |
|
Evidence
|
D144A S-escape mutant was detected with two of the primer sets, while the rtL217R mutant within the Pol - conferring resistance to Adefovir - could be picked up with a different pair of primer sets.
|
|
|
HBV Mutation Detail Information