|
Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV) |
Literature Information
|
PubMed PMID
|
18433023
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2008 |
|
Journal
|
Hepatology (Baltimore, Md.) |
|
Title
|
Safety, efficacy, and pharmacokinetics of adefovir dipivoxil in children and adolescents (age 2 to <18 years) with chronic hepatitis B. |
|
Author
|
Jonas MM,Kelly D,Pollack H,Mizerski J,Sorbel J,Frederick D,Mondou E,Rousseau F,Sokal E |
|
Evidence
|
No subject developed an ADV-associated mutation that has been linked to HBV DNA rebound (that is, mutations rtN236T or rtA181V).
|
|
|
HBV Mutation Detail Information