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Mutation Information
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Mutation Site
|
V214A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV);tenofovir (TDF) |
Literature Information
|
PubMed PMID
|
22505793
|
|
Published Year
|
2011 |
|
Journal
|
International journal of current chemistry |
|
Title
|
Hepatitis B Virus genotypic differences map structurally close to NRTI resistance hot spots. |
|
Author
|
Michailidis E,Singh K,Kirby KA,Hachiya A,Yoo W,Hong SP,Kim SO,Folk WR,Sarafianos SG |
|
Evidence
|
The V214A mutation causes resistance to ADV and TDF and the Q215S mutation causes resistance to LVD, ADV and TDF.
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HBV Mutation Detail Information