|
Mutation Information
|
Mutation Site
|
N236T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.N236T+rt.A181V |
|
Genotype/Subtype
|
C |
|
Relevant Drug
|
adefovir (ADV) |
Literature Information
|
PubMed PMID
|
16461777
|
|
Clinical information
|
Yes
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2006 |
|
Journal
|
Gut |
|
Title
|
Resistance to adefovir dipivoxil in lamivudine resistant chronic hepatitis B patients treated with adefovir dipivoxil. |
|
Author
|
Yeon JE,Yoo W,Hong SP,Chang YJ,Yu SK,Kim JH,Seo YS,Chung HJ,Moon MS,Kim SO,Byun KS,Lee CH |
|
Evidence
|
The rtA181V, rtN236T, and rtA181T mutations were detected in five, four, and two of the 67 patients at treatment months 12-17, 3-19, and 7-20, respectively.
|
|
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HBV Mutation Detail Information