Mutation Information
Mutation Site
|
A181T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
adefovir (ADV) |
Country
|
Italy |
Literature Information
PubMed PMID
|
24589944
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2014 |
Journal
|
La Clinica terapeutica |
Title
|
Lamivudine and Adefovir Motif Variants Detected in chronic Hepatıtıs B patients. |
Author
|
Ozekinci T,Mese S,Ozbek E,Atmaca S |
Evidence
|
This mutations; responsible for lamivudine resistance YMDD+YVDD (n=10), YMDD+YIDD (n=12), YIDD (n=2), YVDD (=1); responsible for adefovir resistance N236T (n=3), A181T (n=5); responsible for lamivudine and adefovir resistance YMDD+YIDD+N236T (n=1).
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