HBV Mutation Detail Information

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Mutation Information
Mutation Site A181T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug adefovir (ADV)
Country Italy
Literature Information
PubMed PMID 24589944
Disease Chronic hepatitis B
Published Year 2014
Journal La Clinica terapeutica
Title Lamivudine and Adefovir Motif Variants Detected in chronic Hepatıtıs B patients.
Author Ozekinci T,Mese S,Ozbek E,Atmaca S
Evidence This mutations; responsible for lamivudine resistance YMDD+YVDD (n=10), YMDD+YIDD (n=12), YIDD (n=2), YVDD (=1); responsible for adefovir resistance N236T (n=3), A181T (n=5); responsible for lamivudine and adefovir resistance YMDD+YIDD+N236T (n=1).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation