HBV Mutation Detail Information

> V173L Search Result


Mutation Information
Mutation Site V173L
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug lamivudine (LAM)
Literature Information
PubMed PMID 14760897
Disease HBV-HIV coinfection
Published Year 2003
Journal Antiviral therapy
Title Monitoring the emergence of hepatitis B virus polymerase gene variants during lamivudine therapy in human immunodeficiency virus coinfected patients: performance of CLIP sequencing and line probe assay.
Author Roque-Afonso AM,Férey MP,Mackiewicz V,Fki L,Dussaix E
Evidence Interestingly, TRUGENE sequencing identified on late samples from three patients a variant carrying rtV173L plus rtL180M plus M204V mutations, having the in vitro characteristics of 'vaccine escape' mutants.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation