HBV Mutation Detail Information

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Mutation Information
Mutation Site T184A
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.T184A+rt.M204V
Genotype/Subtype D
Country Italy+other countries
Literature Information
PubMed PMID 19041149
Disease HBV infection
Published Year 2009
Journal Journal of hepatology
Title The profile of mutational clusters associated with lamivudine resistance can be constrained by HBV genotypes.
Author Svicher V,Gori C,Trignetti M,Visca M,Micheli V,Bernassola M,Salpini R,Gubertini G,Longo R,Niero F,Ceccherini-Silberstein F,De Sanctis GM,Spanò A,Cappiello G,Perno CF
Evidence RtM204V clusters with mutations localized in the RT-B domain (rtV173L, rtL180M, and rtT184A/S) (bootstrap=0.94), while rtM204I clusters with mutations localized in the RT-A domain (rtS53N, rtT54Y, and rtL80I/V) (bootstrap=0.96) (without associations with HBsAg specific mutations).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation