|
Mutation Information
|
Mutation Site
|
A181T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
s.W172*+rt.A181T |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
23166535
|
|
Published Year
|
2012 |
|
Journal
|
Hepatitis monthly |
|
Title
|
Effects of antiviral therapy on the recurrence of hepatocellular carcinoma after curative resection or liver transplantation. |
|
Author
|
Du Y,Su T,Ding Y,Cao G |
|
Evidence
|
However, long-term use of NAs increases the possibility of developing drug-resistant viral mutations such as the HBV rtA181T/sW172 mutation, which increases the risk of HCC recurrence.
|
|
|
HBV Mutation Detail Information