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Mutation Information
|
Mutation Site
|
A836C |
|
Mutation Type
|
Nucleotide level |
|
Gene/Protein/Region Type
|
RT |
|
Nucleotide_Mutation
|
N236T |
|
Country
|
china |
Literature Information
|
PubMed PMID
|
32840739
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2020 |
|
Journal
|
Virus genes |
|
Title
|
An antiviral drug-resistant mutant of hepatitis B virus with high replication capacity in association with a large in-frame deletion in the preS1 region of viral surface gene. |
|
Author
|
Wang T,Qin Y,Zhang J,Li X,Tong S,Zhao W,Zhang J |
|
Evidence
|
The G670A (PCR product and all six clones) and A836C mutations (found in the PCR product and clones c1, c2, c3, and c4) introduced A181T and N236T mutations in the RT domain of the P protein, respectively, which are responsible for ADV resistance
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HBV Mutation Detail Information