HBV Mutation Detail Information

> M204V Search Result

Mutation Information

Mutation Site	M204V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Relevant Drug	lamivudine (LAM);telbivudine (LDT)
Country	Vietnam

Literature Information

PubMed PMID	22720022
Disease	HBV-HCV-HIV coinfection
Published Year	2012
Journal	PloS one
Title	A multicentre molecular analysis of hepatitis B and blood-borne virus coinfections in Viet Nam.
Author	Dunford L,Carr MJ,Dean J,Nguyen LT,Ta Thi TH,Nguyen BT,Connell J,Coughlan S,Nguyen HT,Hall WW,Thi LA
Evidence	78.9% (n = 15/19) of these individuals had undetectable HBV viral loads and, of the 4 patients on HAART with a detectable HBV viral load, one - a HIV/HBV/HCV coinfected IDU - had drug resistance associated mutations, L180M and M204V in the pol gene conferring resistance to lamivudine and possible resistance to telbivudine.

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation