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Mutation Information
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Mutation Site
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L180M |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
RT |
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Combined Mutation
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rt.M204V+rt.A186T+rt.L180M;rt.M204V+rt.A186T+rt.T184S+rt.L180M;rt.M204V+rt.A186T+rt.T184S+rt.L180M;rt.M204V+rt.L180M;rt.M204V+rt.L180M+rt.I163V;rt.M204V+rt.T184S+rt.L180M |
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Country
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China |
Literature Information
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PubMed PMID
|
30796932
|
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Disease
|
HBV infection
|
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Published Year
|
2019 |
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Journal
|
Antiviral research |
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Title
|
Prevalence of the entecavir-resistance-inducing mutation rtA186T in a large cohort of Chinese hepatitis B virus patients. |
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Author
|
Liu L,Liu Y,Chen R,Li X,Luo D,Zhao Y,Li Q,Huang B,Wang FS,Liu X,Xu D |
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Evidence
|
Classical ETV-resistance mutations rtT184/S202/M250substitution+rtM204V/I±L180M (LAM-r), rtA186T, and rtI163V were detected in 1252 (5.69%), 14 (0.06%), and 230 (1.05%) of the 22,009 patients, respectively.
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HBV Mutation Detail Information