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Mutation Information
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Mutation Site
|
L180M |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
23272650
|
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Disease
|
HBV infection
|
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Published Year
|
2012 |
|
Journal
|
BMC microbiology |
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Title
|
Whole genome HBV deletion profiles and the accumulation of preS deletion mutant during antiviral treatment. |
|
Author
|
Zhang D,Dong P,Zhang K,Deng L,Bach C,Chen W,Li F,Protzer U,Ding H,Zeng C |
|
Evidence
|
Meanwhile, no significant difference in deletion occurrence was found between different genders (P = 0.608, FET) or genotypes (P = 0.450, FET). In addition, two out of three preS2 deletion mutants in the antiviral group had known antiviral resistance mutations, M204I and L180M, respectively.
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HBV Mutation Detail Information