HBV Mutation Detail Information

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Mutation Information
Mutation Site I224V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Country China
Literature Information
PubMed PMID 26825915
Disease HBV infection
Published Year 2016
Journal Medicine
Title Dynamics of Genotypic Mutations of the Hepatitis B Virus Associated With Long-Term Entecavir Treatment Determined With Ultradeep Pyrosequencing: A Retrospective Observational Study.
Author Zhang XX,Li MR,Cao Y,Zhang RW,Zhang Y,Li F,Xi HL,Xu XY
Evidence In addition to the common substitutions, unknown amino acid substitutions, such as rtL145 M/S, rtF151Y/L, rtR153Q, rtI224 V, rtN248H, rtS223A, rtS256C, need to be further verified. NAr substitutions are observed at frequencies of 0.10% to 6.7% before therapy.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation