Mutation Information
Mutation Site
|
I224V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Country
|
China |
Literature Information
PubMed PMID
|
26825915
|
Disease
|
HBV infection
|
Published Year
|
2016 |
Journal
|
Medicine |
Title
|
Dynamics of Genotypic Mutations of the Hepatitis B Virus Associated With Long-Term Entecavir Treatment Determined With Ultradeep Pyrosequencing: A Retrospective Observational Study. |
Author
|
Zhang XX,Li MR,Cao Y,Zhang RW,Zhang Y,Li F,Xi HL,Xu XY |
Evidence
|
In addition to the common substitutions, unknown amino acid substitutions, such as rtL145 M/S, rtF151Y/L, rtR153Q, rtI224 V, rtN248H, rtS223A, rtS256C, need to be further verified. NAr substitutions are observed at frequencies of 0.10% to 6.7% before therapy.
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