HBV Mutation Detail Information

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Mutation Information
Mutation Site L180M
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Combined Mutation rt.L180M+rt.M204V
Relevant Drug lamivudine (LAM)
Country Italy
Literature Information
PubMed PMID 21692935
Disease Chronic hepatitis B
Published Year 2011
Journal Journal of viral hepatitis
Title Large-scale survey of naturally occurring HBV polymerase mutations associated with anti-HBV drug resistance in untreated patients with chronic hepatitis B.
Author Mirandola S,Campagnolo D,Bortoletto G,Franceschini L,Marcolongo M,Alberti A
Evidence HBV mutations associated with antiviral drug resistance were detected in 13 (5%) patients: three patients infected with HBV genotype C had the rtM204V + rtL180M mutations associated with lamivudine (LMV) resistance.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation