HBV Mutation Detail Information

> L528M Search Result

Mutation Information

Mutation Site	L528M
Mutation Type	Amino acid level
Gene/Protein/Region Type	P
Relevant Drug	lamivudine (LAM)

Literature Information

PubMed PMID	11584376
Disease	Chronic hepatitis B
Published Year	2001
Journal	Hepatology (Baltimore, Md.)
Title	Factors associated with hepatitis B virus DNA breakthrough in patients receiving prolonged lamivudine therapy.
Author	Yuen MF,Sablon E,Hui CK,Yuan HJ,Decraemer H,Lai CL
Evidence	There was no increase in the rate of development of YMDD variants or L528M mutation in patients receiving lamivudine 25 mg daily or famciclovir 500 mg 3 times a day before being given lamivudine 100 mg daily.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation