HBV Mutation Detail Information

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Mutation Information

Mutation Site	A181T
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.A181T+rt.A194T;rt.M204I+rt.A181T+rt.A194T;rt.M204I+rt.A181T+rt.L80V+rt.A194T;rt.M204I+rt.A181T+rt.L80I+rt.A194T
Relevant Drug	adefovir dipivoxil (ADV);lamivudine (LAM);tenofovir (TFV);tenofovir alafenamide (TAF);entecavir (ETV)

Literature Information

PubMed PMID	32894807
Disease	Chronic hepatitis B
Published Year	2021
Journal	Journal of viral hepatitis
Title	Characterization of Hepatitis B virus polymerase mutations A194T and CYEI and tenofovir disoproxil fumarate or tenofovir alafenamide resistance.
Author	Liu Y,Chang S,Martin R,Flaherty J,Mo H,Feierbach B
Evidence	TABLE 3

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation