|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204I+rt.L180M;rt.M204V+rt.L180M |
|
Genotype/Subtype
|
B;C |
|
Relevant Drug
|
lamivudine (LAM);entecavir (ETV);telbivudine (LDT) |
|
Country
|
Shenzhen，China |
Literature Information
|
PubMed PMID
|
31558731
|
|
Disease
|
HBV infection
|
|
Published Year
|
2019 |
|
Journal
|
Scientific reports |
|
Title
|
Prevalence of Hepatitis B Virus Infection in Shenzhen, China, 2015-2018. |
|
Author
|
Tao J,Zhang W,Yue H,Zhu G,Wu W,Gong W,Fang H,He G,Hu X,Zhao H,Liu A |
|
Evidence
|
NAs resistant mutation occurrence patterns were multitudinous; single mutation patterns of rtM204I/V and rtL180M occurrences accounted for majority, followed by the combinational mutation pattern L180M + M204I/V.
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HBV Mutation Detail Information