|
Mutation Information
|
Mutation Site
|
A181V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
C |
|
Relevant Drug
|
adefovir (ADV);lamivudine (LAM) |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
25303802
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2014 |
|
Journal
|
Antiviral research |
|
Title
|
Different mechanism of selection of adefovir-resistant mutant viruses during adefovir monotherapy in patients with lamivudine-resistant chronic hepatitis B. |
|
Author
|
Cho YK,Cui XJ,Jeong SU,Song BC |
|
Evidence
|
The majority of LMV-resistant mutants harbor the rtM204V/I mutation, while a minor fraction harbor the rtA181V/T mutation.
|
|
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HBV Mutation Detail Information