|
Mutation Information
|
Mutation Site
|
Q215S |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.I266V+rt.D263E+rt.L235F+rt.Q215S+rt.S176W+rt.L164M;rt.Q267H+rt.Y257W+rt.Q215S+rt.R153W;rt.Y257W+rt.N238A+rt.P237T+rt.Q215S+rt.V214A+rt.M204V+rt.L180M+rt.R153W |
|
Genotype/Subtype
|
D |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Rome |
Literature Information
|
PubMed PMID
|
19442845
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2009 |
|
Journal
|
Journal of virological methods |
|
Title
|
A sensitive direct sequencing assay based on nested PCR for the detection of HBV polymerase and surface glycoprotein mutations. |
|
Author
|
Vincenti D,Solmone M,Garbuglia AR,Iacomi F,Capobianchi MR |
|
Evidence
|
Direct sequencing was able to show pol mutations not revealed by DR v2, such as rtV214A, rtQ215H/S, and rtM250V.
|
|
|
HBV Mutation Detail Information