HBV Mutation Detail Information

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Mutation Information

Mutation Site	M250I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT

Literature Information

PubMed PMID	19231002
Clinical information	Yes
Disease	Chronic hepatitis B
Published Year	2009
Journal	Journal of hepatology
Title	Entecavir shows limited efficacy in HBeAg-positive hepatitis B patients with a partial virologic response to adefovir therapy.
Author	Reijnders JG,Pas SD,Schutten M,de Man RA,Janssen HL
Evidence	Two lamivudine-experienced patients demonstrated the rtM204I mutation; no other entecavir-resistant substitutions were detected (rtI169, rtT184, rtS202, and rtM250).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation