HBV Mutation Detail Information

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Mutation Information
Mutation Site A181T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug adefovir (ADV)
Country Spain
Literature Information
PubMed PMID 17988612
Disease Chronic hepatitis B
Published Year 2007
Journal Medicina clinica
Title [Adefovir dipivoxil compassionate use program in Spain: efficacy and resistance analysis].
Author Buti M,Rodríguez Frías F,Calleja JL,Jardí R,Pons F,Crespo J,Casanovas T,Enríquez J,Carnicer F,Romero M,García Bengoechea M,Prieto M,García Samaniego J,Miras M,Pérez Roldán F,Rueda M,Esteban R
Evidence 20% patients developed resistance to adefovir dipivoxil, and the most frequent detected mutations were: A181V, A181T and N236T.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation