HBV Mutation Detail Information

> M550V Search Result


Mutation Information
Mutation Site M550V
Mutation Type Amino acid level
Gene/Protein/Region Type P
Combined Mutation p.M550V+p.L526M+p.V519L
Relevant Drug lamivudine (LAM)
Literature Information
PubMed PMID 10669360
Disease HBV infection
Published Year 2000
Journal The Journal of infectious diseases
Title Selection of multiresistant hepatitis B virus during sequential nucleoside-analogue therapy.
Author Mutimer D,Pillay D,Cook P,Ratcliffe D,O'Donnell K,Dowling D,Shaw J,Elias E,Cane PA
Evidence After addition of famciclovir, population sequencing showed that the predominant species was V519L/L526M/M550V and that the level of isoleucine at position 550 and leucine at position 526 had declined markedly.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation