HBV Mutation Detail Information

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Mutation Information

Mutation Site	M204V
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.M204V+rt.L180M+rt.A194T;rt.M204V+rt.L180M;rt.M204V+rt.L180M+rt.V173L;rt.M204V+rt.L180M+rt.D134E+rt.H126Y+rt.S106C;rt.M204V+rt.L180M+rt.V173L+rt.D134E+rt.H126Y+rt.S106C;rt.M204V+rt.L180M+rt.V173L+rt.L269I+rt.D134E+rt.H126Y+rt.S106C
Relevant Drug	lamivudine (LAM);tenofovir (TFV);tenofovir alafenamide (TAF);entecavir (ETV)

Literature Information

PubMed PMID	32894807
Disease	Chronic hepatitis B
Published Year	2021
Journal	Journal of viral hepatitis
Title	Characterization of Hepatitis B virus polymerase mutations A194T and CYEI and tenofovir disoproxil fumarate or tenofovir alafenamide resistance.
Author	Liu Y,Chang S,Martin R,Flaherty J,Mo H,Feierbach B
Evidence	TABLE 3

Contents
Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation