HBV Mutation Detail Information

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Mutation Information
Mutation Site V173L
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug lamivudine (LAM)
Country Japan
Literature Information
PubMed PMID 25817219
Disease Chronic hepatitis B
Published Year 2015
Journal Journal of hepatology
Title Characterization of novel entecavir resistance mutations.
Author Hayashi S,Murakami S,Omagari K,Matsui T,Iio E,Isogawa M,Watanabe T,Karino Y,Tanaka Y
Evidence The analysis also identified multiple mutations in the reverse transcriptase (RT) that occurred before and after ETV treatment. At baseline (0 month), when the patient was refractory to LAM treatment, serum HBV contained the well-documented LAM resistance mutations rtV173L, rtL180M, and rtM204I

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation