|
Mutation Information
|
Mutation Site
|
D134E |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Country
|
Korea |
Literature Information
|
PubMed PMID
|
23710315
|
|
Clinical information
|
Yes
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2013 |
|
Journal
|
Gut and liver |
|
Title
|
Quasispecies and pre-existing drug-resistant mutations of hepatitis B virus in patients with chronic hepatitis B. |
|
Author
|
Kim DY,Chang HY,Lim SM,Kim SU,Park JY,Kim JK,Lee KS,Han KH,Chon CY,Ahn SH |
|
Evidence
|
In patient 1, 23 of 100 clones (23%) contained T38A+H55A, which was followed by T38A (21%), and E271Q (20%). The predominant HBV quasispecies in patient 2 was R242A (36%), and the remaining were N76D+D134E (20%), D134E+R242A (17%), and D134E (13%).
|
|
|
HBV Mutation Detail Information