|
Mutation Information
|
Mutation Site
|
V173V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
E |
|
Relevant Drug
|
zidovudine (AZT);lamivudine (LAM);efavirenz (EFV) |
|
Country
|
Namibia |
Literature Information
|
PubMed PMID
|
32915862
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2020 |
|
Journal
|
PloS one |
|
Title
|
Hepatitis B virus drug resistance mutations in HIV/HBV co-infected children in Windhoek, Namibia. |
|
Author
|
Tamandjou Tchuem CR,Brandt L,Nel ER,Cotton MF,Matthews P,Kaindjee-Tjituka F,Preiser W,Andersson MI |
|
Evidence
|
Amino acid changes including rtL80I, rtV173L, rtL180M, rtV191I and rtM204I/V in the reverse transcriptase (RT) region of the pol gene, and sE164D, sW182*, sI195M and sW196LS in the overlapping small HBsAg (SHB) region were identified in all eight children.
|
|
|
HBV Mutation Detail Information