HBV Mutation Detail Information

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Mutation Information

Mutation Site	A181T
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	s.W172*+s.W172S+s.W172L+rt.A181T
Relevant Drug	lamivudine (LAM);adefovir (ADV);entecavir (ETV)
Country	China

Literature Information

PubMed PMID	29630974
Disease	HBV infection
Published Year	2018
Journal	Antiviral research
Title	Hepatitis B virus rtA181T/sW172non-stop mutation may increase resistance fold to adefovir- and entecavir-resistant mutants compared to rtA181T/sW172* mutation.
Author	Zhao L,Li X,Cheng Y,Chen R,Shao J,Zhou Y,Li Q,Liao H,Zhao Y,Liu L,Su H,Liu Y,Liu Y,Xu D
Evidence	Hepatitis B virus rtA181T/sW172non-stop mutation may increase resistance fold to adefovir- and entecavir-resistant mutants compared to rtA181T/sW172* mutation.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation