HBV Mutation Detail Information

> M204V Search Result


Mutation Information
Mutation Site M204V
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype D
Relevant Drug lamivudine (LAM)
Literature Information
PubMed PMID 12823591
Clinical information Yes
Disease HBV infection
Published Year 2003
Journal Journal of viral hepatitis
Title YSDD: a novel mutation in HBV DNA polymerase confers clinical resistance to lamivudine.
Author Bozdayi AM,Uzunalimoğlu O,Türkyilmaz AR,Aslan N,Sezgin O,Sahin T,Bozdayi G,Cinar K,Pai SB,Pai R,Bozkaya H,Karayalçin S,Yurdaydin C,Schinazi RF
Evidence Of the seven patients, six were HBeAg positive at baseline, and four had a double mutation consisting of rtM204V and rtL180M, while two had an rtM204I change.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation