|
Mutation Information
|
Mutation Site
|
A181T |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV);adefovir dipivoxil (ADV) |
Literature Information
|
PubMed PMID
|
19119245
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2008 |
|
Journal
|
The Korean journal of hepatology |
|
Title
|
[The efficacy of adefovir dipivoxil monotherapy and the incidence of genotypic resistance to adefovir dipivoxil in patients with lamivudine-resistant chronic hepatitis B infection]. |
|
Author
|
Moon JH,Cho M,Yoon KT,Bae JH,Heo J,Kim GH,Kang DH,Song GA |
|
Evidence
|
And the rtN236T and rtA181T/V mutants in HBV DNA polymerase were identified in 25% and 64% of patients, respectively.
|
|
|
HBV Mutation Detail Information