HBV Mutation Detail Information

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Mutation Information

Mutation Site	S202I
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	rt.L180M+rt.M204V+rt.S202I+rt.T184G;rt.S202I+rt.T184G
Relevant Drug	lamivudine (LAM);entecavir (ETV);tenofovir (TDF);telbivudine (LDT)

Literature Information

PubMed PMID	16673294
Published Year	2006
Journal	Seminars in liver disease
Title	Antiviral drug resistance: clinical consequences and molecular aspects.
Author	Bartholomeusz A,Locarnini SA
Evidence	Modeling of the second group of ETVresistance mutations (rtT184G+tS202I+tM204V+tL180M), reveals an altered geometry of the poly-merase nucleotide binding pocket near the YMDD site

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation