HBV Mutation Detail Information

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Mutation Information
Mutation Site V539I
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Literature Information
PubMed PMID 10762559
Clinical information Yes
Disease Chronic hepatitis B
Published Year 2000
Journal The Journal of infectious diseases
Title Evolution of hepatitis B virus polymerase gene sequence during famciclovir therapy for chronic hepatitis B.
Author Seignères B,Pichoud C,Ahmed SS,Hantz O,Trépo C,Zoulim F
Evidence By contrast, the 2 other mutations, L528M and V539I, detected in responders 23 and 22, respectively, were still present after cessation of treatment, the first mutant as a mixture with wild-type viral genome and the second mutant present as a major variant.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation