|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.L180M+rt.M204V+rt.M204I |
|
Relevant Drug
|
entecavir (ETV);lamivudine (LAM) |
|
Country
|
Turkey |
Literature Information
|
PubMed PMID
|
22224083
|
|
Disease
|
HBV infection
|
|
Published Year
|
2011 |
|
Journal
|
Hepatitis monthly |
|
Title
|
Frequency and mutation patterns of resistance in patients with chronic hepatitis B infection treated with nucleos(t)ide analogs in add-on and switch strategies. |
|
Author
|
Sayan M,Akhan SC,Senturk O |
|
Evidence
|
The most common LAM and ETV resistance mutations were rtM204I/V, rtL180M and rtT184A/I/S, respectively, while rtA181T/V and rtN236T substitutions were the most frequently observed ADV resistance mutations.
|
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HBV Mutation Detail Information