|
Mutation Information
|
Mutation Site
|
L217R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
adefovir (ADV) |
Literature Information
|
PubMed PMID
|
19195324
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2008 |
|
Journal
|
Antiviral therapy |
|
Title
|
Adefovir for chronic hepatitis B treatment: identification of virological markers linked to therapy response. |
|
Author
|
Rodriguez-Frias F,Jardi R,Schaper M,Buti M,Ferrer-Costa C,Tabernero D,Homs M,Esteban R |
|
Evidence
|
CONCLUSIONS: Virological pretreatment characteristics (HBeAg, viral genotype and rtL217R polymorphism) are potentially associated with ADV response.
|
|
|
HBV Mutation Detail Information