Mutation Information
Mutation Site
|
L80I |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Country
|
Italy |
Literature Information
PubMed PMID
|
23796863
|
Disease
|
HBV infection
|
Published Year
|
2013 |
Journal
|
The Journal of infection |
Title
|
Anti-HBV treatment induces novel reverse transcriptase mutations with reflective effect on HBV S antigen. |
Author
|
Cento V,Van Hemert F,Neumann-Fraune M,Mirabelli C,Di Maio VC,Salpini R,Bertoli A,Micheli V,Gubertini G,Romano S,Visca M,De Sanctis GM,Berkhout B,Marino N,Mazzotta F,Cappiello G,Spanò A,Sarrecchia C,Ceccherini-Silberstein F,Andreoni M,Angelico M,Verheyen J,Perno CF,Svicher V |
Evidence
|
In this analysis, the major LMV-resistance mutation rtM204I significantly correlated with either the novel mutation rtS85F (phi = 0.22) and the classical rtL80I/V (phi = 0.41)
|
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