|
Mutation Information
|
Mutation Site
|
I233V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M250L+rt.N236T+rt.I233V+rt.A181T |
Literature Information
|
PubMed PMID
|
19669299
|
|
Published Year
|
2008 |
|
Journal
|
Hepatology international |
|
Title
|
Primary resistance, multidrug resistance, and cross-resistance pathways in HBV as a consequence of treatment failure. |
|
Author
|
Locarnini S |
|
Evidence
|
Finally, in highly drug-experienced patients, clusters of mutations such as rtA181T/I233V/N236T/M250L, all on the one dominant HBV genome, are being detected which are associated with multi-drug resistance.
|
|
|
HBV Mutation Detail Information