HBV Mutation Detail Information

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Mutation Information

Mutation Site	L180M
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Combined Mutation	s.I195M+rt.V214P+rt.M204V+rt.S202C+rt.L180M
Relevant Drug	lamivudine (LAM);telbivudine (LDT);entecavir (ETV)
Country	Turkey

Literature Information

PubMed PMID	21784687
Disease	Chronic hepatitis B
Published Year	2011
Journal	International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases
Title	Antiviral drug-associated potential vaccine-escape hepatitis B virus mutants in Turkish patients with chronic hepatitis B.
Author	Sayan M,Akhan SC
Evidence	Two of the patients detected with ADAPVEMs were treatment-naïve: patient 1 had primary LAM, LdT, and intermediate ETV drug resistance (rtL80I + rtM204I + rtQ215S/sW196L) and patient 2 had primary LAM, LdT, and ETV drug resistance (rtL180 M + rtS202C + rtM204 V + rtV214P/sI195 M).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation