Mutation Information
Mutation Site
|
D134N |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
B;C;D |
Country
|
China;South Korea;Indonesia |
Literature Information
PubMed PMID
|
29713126
|
Published Year
|
2018 |
Journal
|
World journal of gastroenterology |
Title
|
Naturally occurring hepatitis B virus reverse transcriptase mutations related to potential antiviral drug resistance and liver disease progression. |
Author
|
Choi YM,Lee SY,Kim BJ |
Evidence
|
Eight mutations in RT (rtL80I, rtD134N, rtN139K/T/H, rtY141F, rtM204I/V, rtF221Y, rtI224V, and rtM309K) are significantly associated with HCC progression.
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