|
Mutation Information
|
Mutation Site
|
L180M |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.L180M+rt.M204V |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
Cameroon |
Literature Information
|
PubMed PMID
|
26419862
|
|
Disease
|
HBV-HIV coinfection
|
|
Published Year
|
2016 |
|
Journal
|
Current HIV research |
|
Title
|
High Burden of HBV-Infection and Atypical HBV Strains among HIV-infected Cameroonians. |
|
Author
|
Salpini R,Fokam J,Ceccarelli L,Santoro MM,Nanfack A,Sosso SM,Kowo M,Cento V,Torimiro J,Sarmati L,Andreoni M,Colizzi V,Perno CF,Njoya O |
|
Evidence
|
One out of four 3TC-treated participants (25%) analyzed for drug resistance mutations harbored M204V+L180M, associated with HBV resistance to 3TC. RT resistance was not detected among anti-HBV drug-naïve participants.
|
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HBV Mutation Detail Information