|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
C |
|
Relevant Drug
|
lamivudine (LAM) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
22340383
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2011 |
|
Journal
|
Chinese medical journal |
|
Title
|
Characterization of hepatitis B virus genotypes/subgenotypes in 1,301 patients with chronic hepatitis B in North China. |
|
Author
|
Li XD,Wang L,Liu Y,Xu ZH,Dai JZ,Li L,Yao ZT,Xin SJ,Zhao JM,Xu DP |
|
Evidence
|
HBV/C infection had a higher incidence of lamivudine-resistant mutations rtM204I/V (44.9% vs. 30.2%, P < 0.01) and BCP mutations A1762T+G1764A (65.8% vs. 40.0%, P < 0.01) compared with HBV/B infection.
|
|
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HBV Mutation Detail Information