|
Mutation Information
|
Mutation Site
|
M204V |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Genotype/Subtype
|
B;C |
|
Relevant Drug
|
entecavir (ETV);lamivudine (LAM) |
|
Country
|
Singapore |
Literature Information
|
PubMed PMID
|
23023992
|
|
Disease
|
HBV infection
|
|
Published Year
|
2013 |
|
Journal
|
Journal of medical virology |
|
Title
|
Do different lamivudine-resistant hepatitis B genotypes carry the same risk of entecavir resistance? |
|
Author
|
Lee GH,Aung MO,Dan YY,Lee YM,Mak B,Low HC,Lim K,Thwin MA,Tan PS,Lim SG |
|
Evidence
|
The presence of a HBV polymerase rtM204V mutation at the baseline was found to be the major risk factor for adverse outcomes.
|
|
|
HBV Mutation Detail Information