Mutation Information
Mutation Site
|
N236T |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Viral Reference
|
AB042283;
AB033556;
AB033551;
AB033550;
AB014394;
B014378 |
Relevant Drug
|
Adefovir(ADV) |
Country
|
Japan |
Literature Information
PubMed PMID
|
16789011
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2006 |
Journal
|
Journal of medical virology |
Title
|
Changes in viral loads of lamivudine-resistant mutants and evolution of HBV sequences during adefovir dipivoxil therapy. |
Author
|
Suzuki F,Kumada H,Nakamura H |
Evidence
|
Moreover, selection of the rtN236T polymerasemutant was associated with resistance to ADV.
|
|
|