HBV Mutation Detail Information

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Mutation Information
Mutation Site N236T
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug adefovir (ADV);lamivudine (LAM)
Country China
Literature Information
PubMed PMID 21513743
Disease HBV infection
Published Year 2011
Journal Journal of virological methods
Title Detection of lamivudine- or adefovir-resistant hepatitis B virus mutations by a liquid array.
Author Liu H,Mao R,Fan L,Xia J,Li Y,Yin Y,Li X,Zhao X,Guo H,Zhu H,Zhang Y,Kang Y,Zhang J
Evidence A novel polymerase chain reaction (PCR)-Luminex assay was developed for rapid, accurate, and high-throughput detection of the most important hepatitis B virus (HBV) variants, including those with reverse transcriptase (RT) domain L180M, M204I/V, A181T/V/S, I233V and N236T mutations associated with resistance to lamivudine (LAM) or adefovir (ADV).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation