Mutation Information
Mutation Site
|
I233V |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
adefovir (ADV) |
Country
|
Korea |
Literature Information
PubMed PMID
|
24696492
|
Disease
|
Chronic hepatitis B
|
Published Year
|
2014 |
Journal
|
Journal of virology |
Title
|
The impact of the hepatitis B virus polymerase rtA181T mutation on replication and drug resistance is potentially affected by overlapping changes in surface gene. |
Author
|
Ahn SH,Park YK,Park ES,Kim JH,Kim DH,Lim KH,Jang MS,Choe WH,Ko SY,Sung IK,Kwon SY,Kim KH |
Evidence
|
In this study, we analyzed the evolution of drug-resistant mutations and characterized the effects of the rtA181T and rtI233V mutations on viral replication and drug resistance.
|
|
|