HBV Mutation Detail Information

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Mutation Information

Mutation Site	N236T
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Country	Greece

Literature Information

PubMed PMID	23804383
Disease	HBV infection
Published Year	2013
Journal	Journal of clinical microbiology
Title	Ultrasensitive amplification refractory mutation system real-time PCR (ARMS RT-PCR) assay for detection of minority hepatitis B virus-resistant strains in the era of personalized medicine.
Author	Ntziora F,Paraskevis D,Haida C,Manesis E,Papatheodoridis G,Manolakopoulos S,Elefsiniotis I,Karamitros T,Vassilakis A,Hatzakis A
Evidence	The assay showed 100% sensitivity for the detection of mutant variants A181V, T184A, and N236T in samples from 41 chronically HBV-infected patients under antiviral therapy who had developed resistance-associated mutations detected by direct PCR Sanger sequencing.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation