|
Mutation Information
|
Mutation Site
|
T184A |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.L180M+rt.M204V+rt.T184A;rt.L180M+rt.M204I+rt.T184A;rt.L180M+rt.M204I+rt.M204V+rt.T184A;rt.L180M+rt.M204I+rt.M204V+rt.T184L+rt.T184A;rt.L180M+rt.M204V+rt.T184S+rt.T184A;rt.L180M+rt.M204I+rt.T184S+rt.T184A;rt.L180M+rt.M204V+rt.S202G+rt.T184L+rt.T184A;rt.L180M+rt.M204V+rt.S202G+rt.T184A;rt.L180M+rt.M204V+rt.M250V+rt.T184A;rt.M204V+rt.T184A+rt.A181C+rt.L180M;rt.M204V+rt.T184A+rt.L180M |
|
Genotype/Subtype
|
C |
|
Relevant Drug
|
entecavir (ETV);interferon(IFN);lamivudine (LAM);adefovir dipivoxil (ADV);tenofovir (TDF) |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
30866789
|
|
Disease
|
HBV infection
|
|
Published Year
|
2019 |
|
Journal
|
Emerging microbes & infections |
|
Title
|
Hepatitis B virus mutation pattern rtL180M+A181C+M204V may contribute to entecavir resistance in clinical practice. |
|
Author
|
Liu Y,Zhou Y,Li X,Niu M,Chen R,Shao J,Si L,Luo D,Lin Y,Li L,Zhang K,Xiao X,Xu Z,Liu M,Lu M,Zoulim F,Xu D |
|
Evidence
|
Table1
|
|
|
HBV Mutation Detail Information