|
Mutation Information
|
Mutation Site
|
M204I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.M204I+rt.A186T+rt.T184I;rt.M204I+rt.T184I;rt.M250V+rt.M204I+rt.A186T+rt.T184I |
|
Country
|
China |
Literature Information
|
PubMed PMID
|
30796932
|
|
Disease
|
HBV infection
|
|
Published Year
|
2019 |
|
Journal
|
Antiviral research |
|
Title
|
Prevalence of the entecavir-resistance-inducing mutation rtA186T in a large cohort of Chinese hepatitis B virus patients. |
|
Author
|
Liu L,Liu Y,Chen R,Li X,Luo D,Zhao Y,Li Q,Huang B,Wang FS,Liu X,Xu D |
|
Evidence
|
Classical ETV-resistance mutations rtT184/S202/M250substitution+rtM204V/I±L180M (LAM-r), rtA186T, and rtI163V were detected in 1252 (5.69%), 14 (0.06%), and 230 (1.05%) of the 22,009 patients, respectively.
|
|
|
HBV Mutation Detail Information