|
Mutation Information
|
Mutation Site
|
L450P |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
P |
|
Relevant Drug
|
lamivudine (LAM) |
Literature Information
|
PubMed PMID
|
11596084
|
|
Disease
|
HBV infection
|
|
Published Year
|
2001 |
|
Journal
|
Journal of medical virology |
|
Title
|
Residual hepatitis B virus particles in liver transplant recipients receiving lamivudine: PCR quantitation of HBV DNA and ELISA of preS1 antigen. |
|
Author
|
Petit MA,Buffello-Le Guillou D,Roche B,Dussaix E,Duclos-Vallée JC,Féray C,Samuel D |
|
Evidence
|
Among the three patients who did not respond to lamivudine, one had pol mutations (L450P and S550C) that had not been described previously
|
|
|
HBV Mutation Detail Information