HBV Mutation Detail Information

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Mutation Information

Mutation Site	S143A
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT

Literature Information

PubMed PMID	16549970
Disease	HBV-HIV coinfection
Published Year	2006
Journal	AIDS (London, England)
Title	Characteristics of drug resistant HBV in an international collaborative study of HIV-HBV-infected individuals on extended lamivudine therapy.
Author	Matthews GV,Bartholomeusz A,Locarnini S,Ayres A,Sasaduesz J,Seaberg E,Cooper DA,Lewin S,Dore GJ,Thio CL
Evidence	These include mutations at sT114R (rtV112I), sP120T (rtT128N), sP120Q (no polymerase change), sK122K/N (rtN131N/H), sQ129R (no polymerase change), sM133I (rtV142I) sF134L (rtS143A), and sT143M (no polymerase change), in which the overlapping polymerase changes are shown in parentheses.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation