HBV Mutation Detail Information

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Mutation Information
Mutation Site L180M
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Relevant Drug lamivudine (LAM)
Country China
Literature Information
PubMed PMID 26505028
Disease Chronic hepatitis B
Published Year 2015
Journal Journal of nanoscience and nanotechnology
Title A Nanoscale Mutation-Sensitive On/Off Switch Based Assays for the Detection of Hepatitis B Virus Lamivudine-Resistant Mutations.
Author Sun A,Pu W,Zhou C,Zhang R,Liu B,Pan Y,Zhang J,Li P,Lil K
Evidence The purpose of this study was to develop methods for detecting the mutations of YMDD, rtL180M, and rtV173L by nanoscale mutation-sensitive switch consisting of high fidelity polymerase and phosphorothioate-modified allele specific primers.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation